EXPERIMENTAL IMMUNE MEDIATED ARTHRITIS IN RHESUS-MONKEYS - A MODEL FOR HUMAN RHEUMATOID-ARTHRITIS

被引：37

作者：

BAKKER, NPM

VANERCK, MG

ZURCHER, C

FAABER, P

LEMMENS, A

HAZENBERG, M

BONTROP, RE

JONKER, M

机构：

[1] ERASMUS UNIV,DEPT IMMUNOL,3000 DR ROTTERDAM,NETHERLANDS

[2] TNO,IVEG INST,2280 HV RIJSWIJK,NETHERLANDS

[3] CATHOLIC UNIV NIJMEGEN,SINT RADBOUD HOSP,DEPT RHEUMATOL,6525 GA NIJMEGEN,NETHERLANDS

[4] CATHOLIC UNIV NIJMEGEN,SINT RADBOUD HOSP,DEPT RADIOL DIAG,6525 GA NIJMEGEN,NETHERLANDS

来源：

RHEUMATOLOGY INTERNATIONAL | 1990年 / 10卷 / 01期

关键词：

Arthritis; Collagen; Inflammation; Rhesus monkey;

D O I：

10.1007/BF02274777

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The induction of experimental arthritis in rhesus monkeys was studied by intradermal immunization of bovine type II collagen and antigens derived from Mycobacterium tuberculosis, Streptococcus pyogenes, and Eubacterium aerofaciens. The tested bacterial antigens proved to be not arthritogenic. Bovine type II collagen induced clinical arthritis in 50% of the rhesus monkeys. Type II collagen induced arthritis in rhesus monkeys proved to be a potential model to study clinical, serological, histological, genetic, and immunologic features associated with human RA. © 1990 Springer-Verlag.

引用

页码：21 / 29

页数：9

共 39 条

[11] ANTIBODIES TO TYPE-II COLLAGEN IN RELAPSING POLYCHONDRITIS
FOIDART, JM
ABE, S
MARTIN, GR
ZIZIC, TM
BARNETT, EV
LAWLEY, TJ
KATZ, SI
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1978, 299 (22) : 1203 - 1207
[12] EXTRA-INTESTINAL COMPLICATIONS OF CROHNS-DISEASE AND ULCERATIVE-COLITIS - STUDY OF 700 PATIENTS
GREENSTEIN, AJ
JANOWITZ, HD
SACHAR, DB
[J]. MEDICINE, 1976, 55 (05) : 401 - 412
[13] IMMUNOGENETIC CONTROL OF EXPERIMENTAL TYPE-II COLLAGEN-INDUCED ARTHRITIS .1. SUSCEPTIBILITY AND RESISTANCE AMONG INBRED STRAINS OF RATS
GRIFFITHS, MM
EICHWALD, EJ
MARTIN, JH
SMITH, CB
DEWITT, CW
[J]. ARTHRITIS AND RHEUMATISM, 1981, 24 (06): : 781 - 789
[14] HOLMDAHL R, 1988, IMMUNOLOGY, V65, P305
[15] LYMPHOCYTES-T IN COLLAGEN-II-INDUCED ARTHRITIS IN MICE - CHARACTERIZATION OF ARTHRITOGENIC COLLAGEN-II-SPECIFIC T-CELL LINES AND CLONES
HOLMDAHL, R
KLARESKOG, L
RUBIN, K
LARSSON, E
WIGZELL, H
[J]. SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1985, 22 (03) : 295 - 306
[16] HOLOSHITZ J, 1986, LANCET, V2, P305
[17] AUTOANTIBODY SPECIFICITIES OF IMMUNE-COMPLEXES SEQUESTERED IN ARTICULAR-CARTILAGE OF PATIENTS WITH RHEUMATOID-ARTHRITIS AND OSTEO-ARTHRITIS
JASIN, HE
[J]. ARTHRITIS AND RHEUMATISM, 1985, 28 (03): : 241 - 248
[18] Kelley W.N., 1989, TXB RHEUMATOLOGY, P2144
[19] CLINICAL AND HLA STUDIES IN MULTIPLE CASE FAMILIES WITH RHEUMATOID-ARTHRITIS
KHAN, MA
KUSHNER, I
BRAUN, WE
DEJELO, CL
BALLOU, SP
[J]. TISSUE ANTIGENS, 1981, 18 (02): : 136 - 138
[20] PERSISTENCE OF COLLAGEN TYPE-II-SPECIFIC T-CELL CLONES IN THE SYNOVIAL-MEMBRANE OF A PATIENT WITH RHEUMATOID-ARTHRITIS
LONDEI, M
SAVILL, CM
VERHOEF, A
BRENNAN, F
LEECH, ZA
DUANCE, V
MAINI, RN
FELDMANN, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (02) : 636 - 640

← 1 2 3 4 →