ADP-RIBOSYLATION OF SMALL GTP-BINDING PROTEINS BY BACILLUS-CEREUS

被引：36

作者：

JUST, I ^{[1
]}

SCHALLEHN, G ^{[1
]}

AKTORIES, K ^{[1
]}

机构：

[1] UNIV BONN,INST MED MIKROBIOL & IMMUNOL,W-5300 BONN,GERMANY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 183卷 / 03期

关键词：

D O I：

10.1016/S0006-291X(05)80279-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A human pathogenic strain of Bacillus cereus produces an exoenzyme which selectively ADP-ribosylates 20-25 kDa GTP-binding proteins in platelet membranes. Pre-ADP-ribosylation of rho proteins of human platelet membranes with Clostridium botulinum exoenzyme C3 or Clostridium limosum exoenzyme inhibits subsequent ADP-ribosylation by the exoenzyme from B. cereus indicating similar substrate specificity of the transferases. The ADPribosyltransferase from B. cereus reveals no immunological cross-reactivity with C. botulinum C3 and C. limosum exoenzyme. © 1992 Academic Press, Inc.

引用

页码：931 / 936

页数：6

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