MICROCOLIN-A AND MICROCOLIN-B, NEW IMMUNOSUPPRESSIVE PEPTIDES FROM THE BLUE-GREEN-ALGA LYNGBYA-MAJUSCULA

被引：139

作者：

KOEHN, FE

LONGLEY, RE

REED, JK

机构：

[1] Division of Biomedical Marine Research, Harbor Branch Oceanographic Institution, Inc., Ft. Pierce, Florida 34946

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 05期

关键词：

D O I：

10.1021/np50083a009

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Microcolin A [1] and microcolin B [2] are new immunosuppressive lipopeptides isolated from a Venezuelan sample of the blue-green alga Lyngbya majuscula. The microcolins are potent inhibitors of the murine mixed lymphocyte response and murine P-388 leukemia in vitro. Isolation and structure elucidation of 1 and 2 by nmr, mass spectral, and chemical methods are described.

引用

页码：613 / 619

页数：7

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