COMPARATIVE ACTIVITIES OF 8 QUINOLONES AGAINST MEMBERS OF THE BACTEROIDES-FRAGILIS GROUP

被引：14

作者：

BOROBIO, MV

CONEJO, MD

RAMIREZ, E

SUAREZ, AI

PEREA, EJ

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1994年 / 38卷 / 06期

关键词：

D O I：

10.1128/AAC.38.6.1442

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activities of five new quinolones (clinafloxacin [CI-960 or PD-127391], BAY Y 3118, E-4868, E-5065, and E-5068) against 100 Bacteroides fragilis group bacterial isolates were compared with those of ciprofloxacin, ofloxacin, and sparfloxacin. Overall, E-5068 was the most active in vitro (MIC for 90% of isolates tested [MIC(90)], 0.25 mu g/ml); this was followed by clinafloxacin and BAY Y 3118 (MIC(90), 0.5 mu g/ml). Ciprofloxacin, sparfloxacin, and ofloxacin were the least active (MIC(90)s, 64, 16, and 16 mu g/ml, respectively). B. fragilis and Bacteroides caccae were more susceptible than the other members of the B. fragilis group to all of the quinolones tested.

引用

页码：1442 / 1445

页数：4

共 19 条

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