ENZYME-MEDIATED ENANTIOSELECTIVE PREPARATION OF PURE ENANTIOMERS OF THE ANTIVIRAL AGENT 2',3'-DIDEOXY-5-FLUORO-3'-THIACYTIDINE (FTC) AND RELATED-COMPOUNDS

被引：85

作者：

HOONG, LK

STRANGE, LE

LIOTTA, DC

KOSZALKA, GW

BURNS, CL

SCHINAZI, RF

机构：

[1] EMORY UNIV, DEPT CHEM, ATLANTA, GA 30322 USA

[2] BURROUGHS WELLCOME CO, DIV EXPTL THERAPY, RES TRIANGLE PK, NC 27709 USA

[3] EMORY UNIV, SCH MED, DEPT PEDIAT, DECATUR, GA 30033 USA

[4] VET ADM MED CTR, DECATUR, GA 30033 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 21期

关键词：

D O I：

10.1021/jo00047a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Racemic 2',3'-dideoxy-3'-thianucleosides were resolved by enzyme-catalyzed hyd

引用

页码：5563 / 5565

页数：3

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