NOVEL RENIN INHIBITORS - SYNTHESIS OF AMINOSTATINE AND COMPARISON WITH STATINE-CONTAINING ANALOGS

被引：43

作者：

ARROWSMITH, RJ

CARTER, K

DANN, JG

DAVIES, DE

HARRIS, CJ

MORTON, JA

LISTER, P

ROBINSON, JA

WILLIAMS, DJ

机构：

[1] WELLCOME RES LABS,DEPT BIOCHEM,BECKENHAM BR3 3BS,KENT,ENGLAND

[2] UNIV LONDON IMPERIAL COLL SCI & TECHNOL,DEPT CHEM,LONDON SW7 2AY,ENGLAND

[3] UNIV SOUTHAMPTON,DEPT CHEM,SOUTHAMPTON SO9 5NH,HANTS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1986年 / 10期

关键词：

D O I：

10.1039/c39860000755

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：755 / 757

页数：3

共 14 条

[1] HUMAN RENIN - A NEW CLASS OF INHIBITORS [J].

DANN, JG ;

STAMMERS, DK ;

HARRIS, CJ ;

ARROWSMITH, RJ ;

DAVIES, DE ;

HARDY, GW ;

MORTON, JA .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 134 (01) :71-77

[2]

EVANS BE, 1985, J MED CHEM, V28, P1756

[3]

FEHRENTZ JA, 1983, SYNTHESIS-STUTTGART, P676

[4]

Haber E, 1984, J Hypertens, V2, P223

[5] STEREOCHEMICAL ANALYSIS OF PEPTIDE-BOND HYDROLYSIS CATALYZED BY THE ASPARTIC PROTEINASE PENICILLOPEPSIN [J].

JAMES, MNG ;

SIELECKI, AR .

BIOCHEMISTRY, 1985, 24 (14) :3701-3713

[6]

JONES DM, 1985, 9TH US PEPT S TOR

[7] RECEPTOR-BASED DESIGN OF DIHYDROFOLATE-REDUCTASE INHIBITORS - COMPARISON OF CRYSTALLOGRAPHICALLY DETERMINED ENZYME BINDING WITH ENZYME AFFINITY IN A SERIES OF CARBOXY-SUBSTITUTED TRIMETHOPRIM ANALOGS [J].

KUYPER, LF ;

ROTH, B ;

BACCANARI, DP ;

FERONE, R ;

BEDDELL, CR ;

CHAMPNESS, JN ;

STAMMERS, DK ;

DANN, JG ;

NORRINGTON, FEA ;

BAKER, DJ ;

GOODFORD, PJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (10) :1120-1122

[8]

MARCINISZYN J, 1976, J BIOL CHEM, V251, P7088

[9]

MARSHALL GR, 1976, FED PROC, V35, P2494

[10] INHIBITION OF ASPARTIC PROTEASES BY PEPSTATIN AND 3-METHYLSTATINE DERIVATIVES OF PEPSTATIN - EVIDENCE FOR COLLECTED-SUBSTRATE ENZYME-INHIBITION [J].

RICH, DH ;

BERNATOWICZ, MS ;

AGARWAL, NS ;

KAWAI, M ;

SALITURO, FG ;

SCHMIDT, PG .

BIOCHEMISTRY, 1985, 24 (13) :3165-3173

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