ANTINEUTROPHIL CYTOPLASMIC AUTOANTIBODY-POSITIVE CRESCENTIC GLOMERULONEPHRITIS AS A COMPLICATION OF TREATMENT WITH PROPYLTHIOURACIL IN CHILDREN

被引：88

作者：

VOGT, BA

KIM, YK

JENNETTE, JC

FALK, RJ

BURKE, BA

SINAIKO, A

机构：

[1] UNIV MINNESOTA, DEPT PEDIAT, MINNEAPOLIS, MN USA

[2] UNIV MINNESOTA, DEPT LAB MED & PATHOL, MINNEAPOLIS, MN USA

[3] UNIV N CAROLINA, DEPT PATHOL, CHAPEL HILL, NC USA

[4] UNIV N CAROLINA, DEPT MED, CHAPEL HILL, NC USA

来源：

JOURNAL OF PEDIATRICS | 1994年 / 124卷 / 06期

关键词：

D O I：

10.1016/S0022-3476(05)83199-3

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Propylthiouracil, which is commonly used in the treatment of hyperthyroidism, has been associated in adults with antineutrophil cytoplasmic autoantibody, a serologic marker of vasculitis. Severe renal disease has not been reported as a complication of therapy with this drug. We report severe antineutrophil cytoplasmic autoantibody-positive vasculitis in children receiving propylthiourocil, as well as rapidly progressive crescentic glomerulonephritis after administration of this drug.

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页码：986 / 988

页数：3

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