A ONE-POT SYNTHESIS OF NITROHYDROXYLATED PYRROLIDINE AND PIPERIDINE RING-SYSTEMS BY TANDEM MICHAEL-HENRY REACTION

被引：10

作者：

BARCO, A ^{[1
]}

BENETTI, S ^{[1
]}

DERISI, C ^{[1
]}

POLLINI, GP ^{[1
]}

ROMAGNOLI, R ^{[1
]}

ZANIRATO, V ^{[1
]}

机构：

[1] UNIV FERRARA,DIPARTIMENTO SCI FARMACEUT,I-44100 FERRARA,ITALY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 49期

关键词：

D O I：

10.1016/0040-4039(94)88491-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Nitrohydroxylated pyrrolidine and piperidine ring systems are conveniently obtained through a one-pot procedure involving sequential Michael-Henry reaction between nitroethylene and a nitrogen nucleophile incorporating a suitably placed precursor for the generation either reductively or oxidatively of an aldehyde group which is directly trapped in the subsequent nitroaldolization step.

引用

页码：9293 / 9296

页数：4

共 13 条

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