ASYMMETRIC DIHYDROXYLATION (AD) OF N,N-DIALKYL AND N-METHOXY-N-METHYL ALPHA,BETA-UNSATURATED AND BETA,GAMMA-UNSATURATED AMIDES

被引：69

作者：

BENNANI, YL ^{[1
]}

SHARPLESS, KB ^{[1
]}

机构：

[1] Scripps Res Inst, DEPT CHEM, 10666 N TORREY PINES RD, LA JOLLA, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 13期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(00)60350-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric dihydroxylation of alpha,beta- and beta,gamma-unsaturated amides affords the corresponding diols in good yields and excellent enantiomeric excesses. However, both N,N-dialkyl and N-methoxy-N-methyl alpha,beta- and beta,gamma-unsaturated amides require a Modified-AD-mix(TM) formulation to achieve good catalytic turnover rates.

引用

页码：2079 / 2082

页数：4

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