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INDUCING FACTORS IN XENOPUS EARLY EMBRYOS

被引：212
作者：
SLACK, JMW
机构：
[1] Department of Zoology, ICRF Developmental Biology Unit, Oxford University, Oxford, OX1 3PS, South Parks Road
来源：
CURRENT BIOLOGY | 1994年 / 4卷 / 02期
关键词：
D O I：
10.1016/S0960-9822(94)00027-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent results make it possible to postulate credible candidates for each of the known inducing signals that act to determine cell fate during Xenopus early development. Experiments on biological activity, expression patterns and inhibition of function suggest that Vg-1 and Wnt-11 may act as the primary mesoderm-inducing signals,FGF and activin may serve to relay their effects, and noggin may be a major component of the dorsalizing and neural-inducing signals from the organizer. © 1994 Elsevier Science Ltd. All rights reserved.
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页码：116 / 126
页数：11
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