OXIDATION OF ALKENES BY A CHIRAL NON-PORPHYRINIC OXIDIZING CATALYST BASED ON THE BLEOMYCIN-FE(II) COMPLEX

被引：38

作者：

SUGA, A

SUGIYAMA, T

OTSUKA, M

OHNO, M

SUGIURA, Y

MAEDA, K

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

[2] INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

[3] KYOTO UNIV,INST CHEM RES,UJI,KYOTO 611,JAPAN

来源：

TETRAHEDRON | 1991年 / 47卷 / 07期

关键词：

D O I：

10.1016/S0040-4020(01)86376-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthetic model for the metal binding site of bleomycin with 4-dimethylaminopyridine nucleus, namely PYML-8, shows dioxygen activation up to 125% of that of bleomycin. beta-Methylstyrene is oxidated with the Fe(III)-H2O2, Fe(III)-PhIO, or Fe(II)-O2 complex systems of PYML-8 to give a set of products including optically active epoxide. The product composition is dependent on iron, oxygen source, and reducing agent employed, suggesting varied active species generated from each complex system.

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页码：1191 / 1204

页数：14

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