SYNERGISTIC ACTIVITY OF AZITHROMYCIN AND GAMMA INTERFERON IN MURINE TOXOPLASMOSIS

被引：14

作者：

ARAUJO, FG

REMINGTON, JS

机构：

[1] PALO ALTO MED RES FDN,RES INST,DEPT IMMUNOL & INFECT DIS,PALO ALTO,CA 94301

[2] STANFORD UNIV,MED CTR,SCH MED,DEPT MED,DIV INFECT DIS,STANFORD,CA 94305

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1991年 / 35卷 / 08期

关键词：

D O I：

10.1128/AAC.35.8.1672

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A dose of 75 mg of azithromycin per kg of body weight per day combined with a dose of 2-mu-g of gamma interferon per day and administered for 10 days protected at least 40% of mice infected with a lethal inoculum of Toxoplasma gondii. Azithromycin administered alone protected less than 10% of the mice; gamma interferon had no protective effect.

引用

页码：1672 / 1673

页数：2

共 10 条

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ARAUJO, FG
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ISRAELSKI, D
REMINGTON, J
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