CONFORMATIONALLY CONSTRAINED NONPEPTIDE BETA-TURN MIMETICS OF ENKEPHALIN

被引:102
作者
GARDNER, B
NAKANISHI, H
KAHN, M
机构
[1] MOLECUMET INST,2023 120TH AVE NE,BELLEVUE,WA 98005
[2] UNIV WASHINGTON,DEPT PATHOBIOL,SEATTLE,WA 98195
[3] UNIV ILLINOIS,DEPT CHEM,CHICAGO,IL 60680
关键词
D O I
10.1016/S0040-4020(01)90205-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The design synthesis and in vitro biological analysis of a family of conformationally constrained nonpeptide mimetics incorporating a 4-->1 beta-turn prosthetic unit to examine the proposed biological significance of this conformer is described.
引用
收藏
页码:3433 / 3448
页数:16
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