[1] M NENCKI INST EXPTL BIOL,PASTEURA 3,PL-02093 WARSAW,POLAND
[2] MED ACAD WARSAW,DEPT PHYSIOL,PL-02032 WARSAW,POLAND
来源:
MOLECULAR BRAIN RESEARCH
|
1992年
/
14卷
/
04期
关键词:
TRANSCRIPTION FACTOR;
PROTOONCOGENE;
COPULATORY BEHAVIOR;
RAT BRAIN;
MESSENGER RNA LEVEL;
D O I:
10.1016/0169-328X(92)90103-I
中图分类号:
Q189 [神经科学];
学科分类号:
071006 ;
摘要:
An elevated expression of c-fos protooncogene, encoding transcription factor Fos, is known to serve as a useful marker of neuronal activation. In the studies reported in this communication we have used Northern and dot blot techniques to analyze c-fos mRNA levels in male rat brain during the learning of the copulatory behavior. The animals were trained (single ejaculation in a training/testing session) for up to 7 sessions. C-fos mRNA levels have been found to increase in the sensory cortex area following the third and fifth session but not after the first and the last one.