TRANS-ACTING FACTORS INVOLVED IN ADIPOGENIC DIFFERENTIATION

被引：60

作者：

VASSEURCOGNET, M ^{[1
]}

LANE, MD ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV, SCH MED, BALTIMORE, MD 21205 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1993年 / 3卷 / 02期

关键词：

D O I：

10.1016/0959-437X(93)90029-O

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The differentiation of preadipocytes into adipocytes in culture is accompanied by the coordinate transcriptional activation of adipose-specific genes. Recent studies have identified cis-acting elements that are involved in activating (or derepressing) the transcription of many of these genes during differentiation. The identification of key trans-acting nuclear factors that interact with certain of these elements makes it possible to formulate models for the regulatory network governing the adipogenic differentiation program.

引用

页码：238 / 245

页数：8

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