PORTABLE, HIGH-BANDWIDTH FREQUENCY-DOMAIN PHOTON MIGRATION INSTRUMENT FOR TISSUE SPECTROSCOPY

被引：60

作者：

MADSEN, SJ ^{[1
]}

ANDERSON, ER ^{[1
]}

HASKELL, RC ^{[1
]}

TROMBERG, BJ ^{[1
]}

机构：

[1] UNIV CALIF IRVINE,BECKMAN LASER INST & MED CLIN,IRVINE,CA 92715

来源：

OPTICS LETTERS | 1994年 / 19卷 / 23期

关键词：

D O I：

10.1364/OL.19.001934

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe a novel frequency-domain photon migration instrument employing direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical properties of biological tissues in near real time. An infinite medium diffusion model was used to extract absorption and transport scattering coefficients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed to within 10% of those expected.

引用

页码：1934 / 1936

页数：3

共 10 条

[1]

FISHKIN J, 1991, P SOC PHOTO-OPT INS, V1431, P122, DOI 10.1117/12.44184

[2] OPTICAL-PROPERTIES OF INTRALIPID - A PHANTOM MEDIUM FOR LIGHT-PROPAGATION STUDIES [J].

FLOCK, ST ;

JACQUES, SL ;

WILSON, BC ;

STAR, WM ;

VANGEMERT, MJC .

LASERS IN SURGERY AND MEDICINE, 1992, 12 (05) :510-519

[3] THE MEASURED ELECTRICAL-PROPERTIES OF NORMAL AND MALIGNANT HUMAN TISSUES FROM 50 TO 900 MHZ [J].

JOINES, WT ;

ZHANG, Y ;

LI, CX ;

JIRTLE, RL .

MEDICAL PHYSICS, 1994, 21 (04) :547-550

[4]

Lakowicz J. R., 1983, PRINCIPLES FLUORESCE, P51, DOI 10.1007/978-1-4615-7658-7

[5] DETERMINATION OF THE OPTICAL-PROPERTIES OF THE HUMAN UTERUS USING FREQUENCY-DOMAIN PHOTON MIGRATION AND STEADY-STATE TECHNIQUES [J].

MADSEN, SJ ;

WYSS, P ;

SVAASAND, LO ;

HASKELL, RC ;

TADIR, Y ;

TROMBERG, BJ .

PHYSICS IN MEDICINE AND BIOLOGY, 1994, 39 (08) :1191-1202

[6]

OCONNOER DV, 1984, TIME CORRELATED SING, P9

[7] REFRACTION OF DIFFUSE PHOTON DENSITY WAVES [J].

OLEARY, MA ;

BOAS, DA ;

CHANCE, B ;

YODH, AG .

PHYSICAL REVIEW LETTERS, 1992, 69 (18) :2658-2661

[8] PROPERTIES OF PHOTON DENSITY WAVES IN MULTIPLE-SCATTERING MEDIA [J].

TROMBERG, BJ ;

SVAASAND, LO ;

TSAY, TT ;

HASKELL, RC .

APPLIED OPTICS, 1993, 32 (04) :607-616

[9] LIGHT-SCATTERING IN INTRALIPID-10-PERCENT IN THE WAVELENGTH RANGE OF 400-1100 NM [J].

VANSTAVEREN, HJ ;

MOES, CJM ;

VANMARLE, J ;

PRAHL, SA ;

VANGEMERT, MJC .

APPLIED OPTICS, 1991, 30 (31) :4507-4514

[10] LARGE-SIGNAL NONLINEAR DISTORTION PREDICTION FOR A SINGLE-MODE LASER DIODE UNDER MICROWAVE INTENSITY MODULATION [J].

WAY, WI .

JOURNAL OF LIGHTWAVE TECHNOLOGY, 1987, 5 (03) :305-315

← 1 →