STRUCTURE OF RECOMBINANT HUMAN RENIN, A TARGET FOR CARDIOVASCULAR-ACTIVE DRUGS, AT 2.5 A RESOLUTION

被引：211

作者：

SIELECKI, AR

HAYAKAWA, K

FUJINAGA, M

MURPHY, MEP

FRASER, M

MUIR, AK

CARILLI, CT

LEWICKI, JA

BAXTER, JD

JAMES, MNG

机构：

[1] CALIF BIOTECHNOL INC,MT VIEW,CA 94043

[2] UNIV CALIF SAN FRANCISCO,METAB RES UNIT,SAN FRANCISCO,CA 94143

来源：

SCIENCE | 1989年 / 243卷 / 4896期

关键词：

D O I：

10.1126/science.2493678

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1346 / 1351

页数：6

共 44 条

[1] 3-DIMENSIONAL STRUCTURE OF HUMAN RENIN [J].

AKAHANE, K ;

UMEYAMA, H ;

NAKAGAWA, S ;

MORIGUCHI, I ;

HIROSE, S ;

IIZUKA, K ;

MURAKAMI, K .

HYPERTENSION, 1985, 7 (01) :3-12

[2]

BARRY CD, 1976, 229 WASH U COMP SYST

[3] STRUCTURAL AND FUNCTIONAL-ASPECTS OF DOMAIN MOTIONS IN PROTEINS [J].

BENNETT, WS ;

HUBER, R .

CRC CRITICAL REVIEWS IN BIOCHEMISTRY, 1984, 15 (04) :291-384

[4] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES [J].

BERNSTEIN, FC ;

KOETZLE, TF ;

WILLIAMS, GJB ;

MEYER, EF ;

BRICE, MD ;

RODGERS, JR ;

KENNARD, O ;

SHIMANOUCHI, T ;

TASUMI, M .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 112 (03) :535-542

[5] 3-DIMENSIONAL STRUCTURE, SPECIFICITY AND CATALYTIC MECHANISM OF RENIN [J].

BLUNDELL, T ;

SIBANDA, BL ;

PEARL, L .

NATURE, 1983, 304 (5923) :273-275

[6] 4-FOLD STRUCTURAL REPEAT IN THE ACID PROTEASES [J].

BLUNDELL, TL ;

SEWELL, BT ;

MCLACHLAN, AD .

BIOCHIMICA ET BIOPHYSICA ACTA, 1979, 580 (01) :24-31

[7] CRYSTALLOGRAPHIC R-FACTOR REFINEMENT BY MOLECULAR-DYNAMICS [J].

BRUNGER, AT ;

KURIYAN, J ;

KARPLUS, M .

SCIENCE, 1987, 235 (4787) :458-460

[8]

CARILLI CT, 1988, J CHROMATOGR, V444, P203

[9] CHARACTERIZATION OF RECOMBINANT HUMAN PRORENIN AND RENIN [J].

CARILLI, CT ;

VIGNE, JL ;

WALLACE, LC ;

SMITH, LM ;

WONG, MA ;

LEWICKI, JA ;

BAXTER, JD .

HYPERTENSION, 1988, 11 (06) :713-716

[10] CONSTRUCTION OF A MODEL FOR THE 3-DIMENSIONAL STRUCTURE OF HUMAN RENAL RENIN [J].

CARLSON, W ;

KARPLUS, M ;

HABER, E .

HYPERTENSION, 1985, 7 (01) :13-26

← 1 2 3 4 5 →