PURIFICATION AND CHARACTERIZATION OF THE RAT-LIVER MICROSOMAL CYTOCHROME-P-450 INVOLVED IN THE 4-HYDROXYLATION OF DEBRISOQUINE, A PROTOTYPE FOR GENETIC-VARIATION IN OXIDATIVE DRUG-METABOLISM

被引：198

作者：

LARREY, D

DISTLERATH, LM

DANNAN, GA

WILKINSON, GR

GUENGERICH, FP

机构：

[1] VANDERBILT UNIV,MED CTR,SCH MED,DEPT BIOCHEM,NASHVILLE,TN 37232

[2] VANDERBILT UNIV,MED CTR,SCH MED,CTR ENVIRONM TOXICOL,NASHVILLE,TN 37232

[3] VANDERBILT UNIV,MED CTR,SCH MED,DEPT PHARMACOL,NASHVILLE,TN 37232

来源：

BIOCHEMISTRY | 1984年 / 23卷 / 12期

关键词：

D O I：

10.1021/bi00307a039

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：2787 / 2795

页数：9

共 42 条

[1] ANIMAL MODELING OF HUMAN POLYMORPHIC DRUG OXIDATION - THE METABOLISM OF DEBRISOQUINE AND PHENACETIN IN RAT INBRED STRAINS
ALDABBAGH, SG
IDLE, JR
SMITH, RL
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1981, 33 (03) : 161 - 164
[2] BOOBIS AR, 1983, MOL PHARMACOL, V23, P474
[3] CLEVELAND DW, 1977, J BIOL CHEM, V252, P1102
[4] EVIDENCE FOR AN ENZYMATIC DEFECT IN THE 4-HYDROXYLATION OF DEBRISOQUINE BY HUMAN-LIVER
DAVIES, DS
KAHN, GC
MURRAY, S
BRODIE, MJ
BOOBIS, AR
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 11 (01) : 89 - 91
[5] THE CONTRIBUTION OF GENETICALLY-DETERMINED OXIDATION STATUS TO INTERINDIVIDUAL VARIATION IN PHENACETIN DISPOSITION
DEVONSHIRE, HW
KONG, I
COOPER, M
SLOAN, TP
IDLE, JR
SMITH, RL
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 16 (02) : 157 - 166
[6] ANTIPYRINE METABOLISM IN RELATION TO POLYMORPHIC OXIDATIONS OF SPARTEINE AND DEBRISOQUINE
EICHELBAUM, M
BERTILSSON, L
SAWE, J
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 15 (03) : 317 - 321
[7] EICHELBAUM M, 1982, CLIN PHARMACOKINET, V7, P1, DOI 10.2165/00003088-198207010-00001
[8] PROCEDURE FOR ESTIMATION OF MICROGRAM QUANTITIES OF TRITON X-100
GAREWAL, HS
[J]. ANALYTICAL BIOCHEMISTRY, 1973, 54 (02) : 319 - 324
[9] PRIMARY AND BETA-SECONDARY DEUTERIUM-ISOTOPE EFFECTS IN O-DEETHYLATION OF PHENACETIN
GARLAND, WA
NELSON, SD
SASAME, HA
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1976, 72 (02) : 539 - 545
[10] SPECTROPHOTOMETRIC ASSAY FOR POLYETHOXY NONIONIC DETERGENTS IN MEMBRANE EXTRACTS - CRITIQUE
GOLDSTEIN, S
BLECHER, M
[J]. ANALYTICAL BIOCHEMISTRY, 1975, 64 (01) : 130 - 135

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