LIGAND-INDUCED STRUCTURAL CONSTRAINTS IN HUMAN DIHYDROFOLATE-REDUCTASE REVEALED BY PEPTIDE-SPECIFIC ANTIBODIES

被引：11

作者：

RATNAM, M ^{[1
]}

TAN, X ^{[1
]}

PRENDERGAST, NJ ^{[1
]}

SMITH, PL ^{[1
]}

FREISHEIM, JH ^{[1
]}

机构：

[1] MED COLL OHIO,DEPT BIOCHEM,CS NUMBER 10008,TOLEDO,OH 43699

来源：

BIOCHEMISTRY | 1988年 / 27卷 / 13期

关键词：

D O I：

10.1021/bi00413a033

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：4800 / 4804

页数：5

共 34 条

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[32] THE REACTIVITY OF ANTI-PEPTIDE ANTIBODIES IS A FUNCTION OF THE ATOMIC MOBILITY OF SITES IN A PROTEIN [J].

TAINER, JA ;

GETZOFF, ED ;

ALEXANDER, H ;

HOUGHTEN, RA ;

OLSON, AJ ;

LERNER, RA ;

HENDRICKSON, WA .

NATURE, 1984, 312 (5990) :127-134

[33] LOCATION OF CONTINUOUS ANTIGENIC DETERMINANTS IN THE PROTRUDING REGIONS OF PROTEINS [J].

THORNTON, JM ;

EDWARDS, MS ;

TAYLOR, WR ;

BARLOW, DJ .

EMBO JOURNAL, 1986, 5 (02) :409-413

[34] CORRELATION BETWEEN SEGMENTAL MOBILITY AND THE LOCATION OF ANTIGENIC DETERMINANTS IN PROTEINS [J].

WESTHOF, E ;

ALTSCHUH, D ;

MORAS, D ;

BLOOMER, AC ;

MONDRAGON, A ;

KLUG, A ;

VANREGENMORTEL, MHV .

NATURE, 1984, 311 (5982) :123-126

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