SYNTHETIC ANALYTICAL STUDIES ON ORGANIC-REAGENTS FOR BIOMATERIALS

''Synthetic analytical chemistry: Analytical chemistry with the aid of synthetic organic chemistry'' is proposed by the present author as a new field of analytical chemistry. Such chemistry is developing on the basis of investigations of pi-electron systems such as non-benzenoid aromatics (e.g. annulenes) or conjugated polyene and polyyne systems. Various kinds of organic reagents for analyses (ultraviolet/visible and near-infrared absorption, fluorescence, chemiluminescence and new silica gel column packings for high-performance liquid chromatography) were developed and applied to the analyses of many biomaterials. In this paper, synthetic analytical chemistry is illustrated mainly by the author's own studies.