MUCIN-ASSOCIATED SIALOSYL-TN ANTIGEN EXPRESSION IN GASTRIC-CANCER CORRELATES WITH AN ADVERSE OUTCOME

被引：61

作者：

WERTHER, JL

RIVERAMACMURRAY, S

BRUCKNER, H

TATEMATSU, M

ITZKOWITZ, SH

机构：

[1] MT SINAI SCH MED, DEPT MED, GASTROINTESTINAL RES LAB, NEW YORK, NY 10029 USA

[2] MT SINAI SCH MED, DEPT NEOPLAST DIS, NEW YORK, NY 10029 USA

[3] AICHI CANC CTR, RES INST, PATHOL LAB, NAGOYA, AICHI 464, JAPAN

来源：

BRITISH JOURNAL OF CANCER | 1994年 / 69卷 / 03期

关键词：

D O I：

10.1038/bjc.1994.114

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The expression of sialosyl-Tn (STn) antigen was evaluated by immunohistochemistry in primary gastric cancers. Twenty-one of 31 (68%) gastric cancers expressed STn, regardless of tumour location, stage or histological type. Eighty-one per cent of patients with STn-positive tumours died of their disease or had recurrent cancer, compared with 20% of patients with STn-negative tumours (P<0.002). STn may be a useful prognostic marker in patients with gastric cancer.

引用

页码：613 / 616

页数：4

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