VISUAL EVOKED-POTENTIALS IN ALZHEIMERS-DISEASE - CORRELATIONS WITH AGE AND SEVERITY

被引：60

作者：

PHILPOT, MP ^{[1
]}

AMIN, D ^{[1
]}

LEVY, R ^{[1
]}

机构：

[1] INST PSYCHIAT, OLD AGE PSYCHIAT SECT, LONDON SE5 8AF, ENGLAND

来源：

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY | 1990年 / 77卷 / 05期

关键词：

Age; Alzheimer's disease; Severity; Visual evoked potentials;

D O I：

10.1016/0168-5597(90)90053-G

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Flash and pattern reversal visually evoked potentials were recorded in 25 patients fulfilling NINCDS-ADRDA criteria for 'probable' Alzheimer's disease (AD). Results were compared with those obtained from groups of normal elderly subjects and patients with mild memory impairment not amounting to dementia. The P2 component of the flash VEP was significantly delayed in AD patients of 74 years or less and correlated with severity whereas the P100 component of the pattern reversal VEP remained relatively unchanged. The latency difference between the P2 and the P100 proved to be a valid discriminator between demented and non-demented subjects only in the younger age group. This limits its usefulness as a diagnostic test of dementia in patients over the age of 75. © 1990.

引用

页码：323 / 329

页数：7

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