学术探索
学术期刊
新闻热点
数据分析
智能评审

MUTATION OF THE INSULIN-RECEPTOR AT TYROSINE-960 INHIBITS SIGNAL TRANSMISSION BUT DOES NOT AFFECT ITS TYROSINE KINASE-ACTIVITY

被引：350
作者：
WHITE, MF
LIVINGSTON, JN
BACKER, JM
LAURIS, V
DULL, TJ
ULLRICH, A
KAHN, CR
机构：
[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115
[2] GENENTECH INC,DEPT DEV BIOL,S SAN FRANCISCO,CA 94080
来源：
CELL | 1988年 / 54卷 / 05期
关键词：
D O I：
10.1016/S0092-8674(88)80008-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：641 / 649
页数：9
相关论文
共 51 条
  • [1] INSULIN-ACTIVATED TYROSINE PHOSPHORYLATION OF A 15-KILODALTON PROTEIN IN INTACT 3T3-L1 ADIPOCYTES
    BERNIER, M
    LAIRD, DM
    LANE, MD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (07) : 1844 - 1848
  • [2] CHOU CK, 1987, J BIOL CHEM, V262, P1842
  • [3] CRETTAZ M, 1984, J BIOL CHEM, V259, P1543
  • [4] ANALYSIS OF INSULIN ACTION USING DIFFERENTIATED AND DEDIFFERENTIATED HEPATOMA-CELLS
    CRETTAZ, M
    KAHN, CR
    [J]. ENDOCRINOLOGY, 1983, 113 (04) : 1201 - 1209
  • [5] Davis L. G., 1986, BASIC METHODS MOL BI
  • [6] THE HUMAN INSULIN-RECEPTOR CDNA - THE STRUCTURAL BASIS FOR HORMONE-ACTIVATED TRANSMEMBRANE SIGNALING
    EBINA, Y
    ELLIS, L
    JARNAGIN, K
    EDERY, M
    GRAF, L
    CLAUSER, E
    OU, JH
    MASIARZ, F
    KAN, YW
    GOLDFINE, ID
    ROTH, RA
    RUTTER, WJ
    [J]. CELL, 1985, 40 (04) : 747 - 758
  • [7] REPLACEMENT OF LYSINE RESIDUE 1030 IN THE PUTATIVE ATP-BINDING REGION OF THE INSULIN-RECEPTOR ABOLISHES INSULIN-STIMULATED AND ANTIBODY-STIMULATED GLUCOSE-UPTAKE AND RECEPTOR KINASE-ACTIVITY
    EBINA, Y
    ARAKI, E
    TAIRA, M
    SHIMADA, F
    MORI, M
    CRAIK, CS
    SIDDLE, K
    PIERCE, SB
    ROTH, RA
    RUTTER, WJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (03) : 704 - 708
  • [8] EXPRESSION OF A FUNCTIONAL HUMAN INSULIN-RECEPTOR FROM A CLONED CDNA IN CHINESE-HAMSTER OVARY CELLS
    EBINA, Y
    EDERY, M
    ELLIS, L
    STANDRING, D
    BEAUDOIN, J
    ROTH, RA
    RUTTER, WJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (23) : 8014 - 8018
  • [9] REPLACEMENT OF INSULIN-RECEPTOR TYROSINE RESIDUES 1162 AND 1163 COMPROMISES INSULIN-STIMULATED KINASE-ACTIVITY AND UPTAKE OF 2-DEOXYGLUCOSE
    ELLIS, L
    CLAUSER, E
    MORGAN, DO
    EDERY, M
    ROTH, RA
    RUTTER, WJ
    [J]. CELL, 1986, 45 (05) : 721 - 732
  • [10] HETEROLOGOUS TRANSMEMBRANE SIGNALING BY A HUMAN INSULIN-RECEPTOR V-ROS HYBRID IN CHINESE-HAMSTER OVARY CELLS
    ELLIS, L
    MORGAN, DO
    JONG, SM
    WANG, LH
    ROTH, RA
    RUTTER, WJ
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (15) : 5101 - 5105
123456