STRUCTURAL DIFFERENCES BETWEEN WILD-TYPE NADP-DEPENDENT GLUTATHIONE-REDUCTASE FROM ESCHERICHIA-COLI AND A REDESIGNED NAD-DEPENDENT MUTANT

被引：29

作者：

MITTL, PRE ^{[1
]}

BERRY, A ^{[1
]}

SCRUTTON, NS ^{[1
]}

PERHAM, RN ^{[1
]}

SCHULZ, GE ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CAMBRIDGE CTR MOLEC RECOGNIT,DEPT BIOCHEM,CAMBRIDGE CB2 1QW,ENGLAND

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1993年 / 231卷 / 02期

关键词：

X-RAY STRUCTURE; GLUTATHIONE REDUCTASE; PROTEIN ENGINEERING; COENZYME SPECIFICITY; NAD(P)H;

D O I：

10.1006/jmbi.1993.1274

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：191 / 195

页数：5

共 23 条

[1] THE STRUCTURE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE REFINED AT 2.5 A RESOLUTION [J].

ADAMS, MJ ;

GOVER, S ;

LEABACK, R ;

PHILLIPS, C ;

SOMERS, DO .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1991, 47 :817-820

[2] SUBUNIT ASSEMBLY AND ACTIVE-SITE LOCATION IN THE STRUCTURE OF GLUTAMATE-DEHYDROGENASE [J].

BAKER, PJ ;

BRITTON, KL ;

ENGEL, PC ;

FARRANTS, GW ;

LILLEY, KS ;

RICE, DW ;

STILLMAN, TJ .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1992, 12 (01) :75-86

[3] STRUCTURAL CONSEQUENCES OF SEQUENCE PATTERNS IN THE FINGERPRINT REGION OF THE NUCLEOTIDE BINDING FOLD - IMPLICATIONS FOR NUCLEOTIDE SPECIFICITY [J].

BAKER, PJ ;

BRITTON, KL ;

RICE, DW ;

ROB, A ;

STILLMAN, TJ .

JOURNAL OF MOLECULAR BIOLOGY, 1992, 228 (02) :662-671

[4] CRYSTALLOGRAPHIC R-FACTOR REFINEMENT BY MOLECULAR-DYNAMICS [J].

BRUNGER, AT ;

KURIYAN, J ;

KARPLUS, M .

SCIENCE, 1987, 235 (4787) :458-460

[5] THE 3-DIMENSIONAL STRUCTURE OF GLUTATHIONE-REDUCTASE FROM ESCHERICHIA-COLI AT 3.0 A RESOLUTION [J].

ERMLER, U ;

SCHULZ, GE .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1991, 9 (03) :174-179

[6] AN ASPARTATE RESIDUE IN YEAST ALCOHOL DEHYDROGENASE-I DETERMINES THE SPECIFICITY FOR COENZYME [J].

FAN, F ;

LORENZEN, JA ;

PLAPP, BV .

BIOCHEMISTRY, 1991, 30 (26) :6397-6401

[7] A SINGLE AMINO-ACID SUBSTITUTION IN LACTATE-DEHYDROGENASE IMPROVES THE CATALYTIC EFFICIENCY WITH AN ALTERNATIVE COENZYME [J].

FEENEY, R ;

CLARKE, AR ;

HOLBROOK, JJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1990, 166 (02) :667-672

[8] IMPROVEMENT OF LIMIT OF DIFFRACTION AND USEFUL X-RAY LIFETIME OF CRYSTALS OF GLYCOGEN DEBRANCHING ENZYME [J].

FITZGERALD, PMD ;

MADSEN, NB .

JOURNAL OF CRYSTAL GROWTH, 1986, 76 (03) :600-606

[9] GLUTATHIONE-REDUCTASE FROM ESCHERICHIA-COLI - CLONING AND SEQUENCE-ANALYSIS OF THE GENE AND RELATIONSHIP TO OTHER FLAVOPROTEIN DISULFIDE OXIDOREDUCTASES [J].

GREER, S ;

PERHAM, RN .

BIOCHEMISTRY, 1986, 25 (09) :2736-2742

[10] CDNA SEQUENCE OF ADRENODOXIN REDUCTASE - IDENTIFICATION OF NADP-BINDING SITES IN OXIDOREDUCTASES [J].

HANUKOGLU, I ;

GUTFINGER, T .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1989, 180 (02) :479-484

← 1 2 3 →