PROPERTIES OF SINGLE NA+-ACTIVATED K+ CHANNELS IN CULTURED CENTRAL NEURONS OF THE CHICK-EMBRYO

被引：14

作者：

DRYER, SE

机构：

[1] Program in Neuroscience, Department of Biological Science B-221, Florida State University, Tallahassee

来源：

NEUROSCIENCE LETTERS | 1993年 / 149卷 / 02期

关键词：

K+ CHANNEL; PATCH CLAMP; EDINGER-WESTPHAL NUCLEUS; OLFACTORY BULB;

D O I：

10.1016/0304-3940(93)90754-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Na+-activated K+ channels (I(K[Na])) of cultured chick brainstem neurons do not run down following excision of inside-out patches, but this occurs within seconds to minutes in cultured chick olfactory bulb neurons. I(K[Na]) channels of chick brainstem neurons exhibit a main conductance state of 95-105 pS, and also express multiple sub-conductance states. These channels have complex kinetics, with multiple closed and main conductance states. The average lifetime of the main conductance state is not dependent on the Na+ concentration used to activate the channels.

引用

页码：133 / 136

页数：4

共 17 条

[11] INTRACELLULAR NA+ ACTIVATES A K+ CHANNEL IN MAMMALIAN CARDIAC-CELLS [J].