CATABOLITE REPRESSION OF BETA-GLUCANASE SYNTHESIS IN BACILLUS-SUBTILIS

被引：43

作者：

KRUGER, S ^{[1
]}

STULKE, J ^{[1
]}

HECKER, M ^{[1
]}

机构：

[1] ERNST MORITZ ARNDT UNIV GREIFSWALD, INST MIKROBIOL & MOLEK BIOL, FACHRICHTUNG BIOL, JAHNSTR 15, D-17487 GREIFSWALD, GERMANY

来源：

JOURNAL OF GENERAL MICROBIOLOGY | 1993年 / 139卷

关键词：

D O I：

10.1099/00221287-139-9-2047

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Beta-Glucanase synthesis in Bacillus subtilis was repressed by glucose and other substrates of glycolysis. Experiments with different pts mutants showed that the phosphoenolpyruvate: sugar phosphotransferase system is not involved in carbon catabolite repression of beta-glucanase synthesis. Carbon catabolite repression of beta-glucanase synthesis was completely abolished in a ccpA mutant. An operator structure similar to those upstream of amyE and the xyl operon was found and was shown by site-directed mutagenesis to be the target for carbon catabolite repression of beta-glucanase synthesis. The presence of this operator on a multi-copy plasmid resulted in a reduced repression of both beta-glucanase and alpha-amylase synthesis. It seems likely that the gene encoding these enzymes are part of one regulon with respect to catabolite repression.

引用

页码：2047 / 2054

页数：8

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