Behavioural changes in the rat following infection with varicella-zoster virus

被引:65
作者
Fleetwood-Walker, SM
Quinn, JP
Wallace, C
Blackburn-Munro, G
Kelly, BG
Fiskerstrand, CE
Nash, AA
Dalziel, RG [1 ]
机构
[1] Univ Edinburgh, Royal Dick Sch Vet Studies, Dept Vet Pathol, Edinburgh EH9 1QH, Midlothian, Scotland
[2] Univ Edinburgh, Royal Dick Sch Vet Studies, Dept Preclin Vet Sci, Edinburgh EH9 1QH, Midlothian, Scotland
基金
英国惠康基金;
关键词
D O I
10.1099/0022-1317-80-9-2433
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Following the establishment of a chronic varicella-zoster virus infection in the rat, behavioural allodynia and hyperalgesia were observed in the injected, but not the contralateral hind limb up to 33 days post-infection. This model may prove useful in investigating mechanisms involved in the establishment of post-herpetic neuralgia.
引用
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页码:2433 / 2436
页数:4
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