TEMPORAL DISTRIBUTION OF HUMAN ROTAVIRUS SEROTYPE-1, SEROTYPE-2, SEROTYPE-3, AND SEROTYPE-4 IN VENEZUELAN CHILDREN WITH GASTROENTERITIS DURING 1979-1989

被引：24

作者：

WHITE, L

GARCIA, D

BOHER, Y

BLANCO, M

PEREZ, M

ROMER, H

FLORES, J

PEREZSCHAEL, I

机构：

[1] UNIV CENT VENEZUELA,MINIST SANIDAD & ASISTENCIA SOCIAL,INST BIOMED,AP 4043,CARACAS 1010A,VENEZUELA

[2] HOSP NINOS JM DE LOS RIOS,CARACAS,VENEZUELA

[3] NIH,INFECT DIS LAB,BETHESDA,MD 20892

来源：

JOURNAL OF MEDICAL VIROLOGY | 1991年 / 34卷 / 02期

关键词：

ROTAVIRUS; DIARRHEA; DISEASE;

D O I：

10.1002/jmv.1890340202

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remaining 129 (30.21%) samples could not be determined. Of the specimens typed, 85 (19.90% of the total) were serotype 1, 43 (10.07%) were serotype 2, 105 (24.59%) were serotype 3, and 65 (15.22%) were serotype 4. Yearly changes in the frequency of individual serotypes were observed. The predominance of a single serotype with minor contribution from others was noted every year. In this study, serotype 1 appears to induce a less severe illness in comparison with serotypes 2,3, and 4. No apparent association between the proportion of each serotype and the children's age were found.

引用

页码：79 / 84

页数：6

共 23 条

[21] RELATIVE FREQUENCY OF ROTAVIRUS SUBGROUP-1 AND SUBGROUP-2 IN VENEZUELAN CHILDREN WITH GASTROENTERITIS AS ASSAYED WITH MONOCLONAL-ANTIBODIES [J].