ACTIVATION MEMBRANE-RECEPTORS

被引:41
作者
JI, TH
MURDOCH, WJ
JI, I
机构
[1] Department of Molecular Biology, University of Wyoming, Laramie, 82071-3944, Wyoming
来源
ENDOCRINE | 1995年 / 3卷 / 03期
关键词
HORMONE RECEPTORS; RECEPTOR ACTIVATION; SIGNAL GENERATION; TRANSMEMBRANE SIGNAL TRANSFER;
D O I
10.1007/BF02994442
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Many extracellular messengers interact with discriminate receptors on the cell surface. Some of bound ligands activate receptors whereas others fail to do so. Only activated receptors are capable of generating and transferring signal through the membrane. Recent advances in our understanding of agonist-induced and constitutive receptor activation suggest several molecular mechanisms for receptor activation, signal generation and transmembrane signal transfer.
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页码:187 / 194
页数:8
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