TOTAL SYNTHESIS OF THE STRYCHNOS ALKALOID TUBOTAIWINE

被引：18

作者：

GRACIA, J ^{[1
]}

BONJOCH, J ^{[1
]}

CASAMITJANA, N ^{[1
]}

AMAT, M ^{[1
]}

BOSCH, J ^{[1
]}

机构：

[1] UNIV BARCELONA,FAC PHARM,ORGAN CHEM LAB,E-08028 BARCELONA,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 09期

关键词：

D O I：

10.1039/c39910000614

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The total synthesis of racemic tubotaiwine 8 has been achieved from the tetracyclic intermediate 1, the key steps being the construction of the C(7)-quaternary centre by cyclization of a thionium ion upon the indole 3-position and the introduction of the C(16)-methoxycarbonyl substituent by photochemical rearrangement of the N-methoxycarbonyleamine 7.

引用

页码：614 / 615

页数：2

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