BIVALENT LIGANDS AND THE MESSAGE-ADDRESS CONCEPT IN THE DESIGN OF SELECTIVE OPIOID RECEPTOR ANTAGONISTS

被引：241

作者：

PORTOGHESE, PS

机构：

来源：

关键词：

D O I：

10.1016/0165-6147(89)90267-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：230 / 235

页数：6

共 28 条

[1] BINDING OF FLEXIBLE LIGANDS TO MACROMOLECULES
BURGEN, ASV
ROBERTS, GCK
FEENEY, J
[J]. NATURE, 1975, 253 (5494) : 753 - 755
[2] SPECIFIC RECEPTOR FOR THE OPIOID PEPTIDE DYNORPHIN - STRUCTURE-ACTIVITY-RELATIONSHIPS
CHAVKIN, C
GOLDSTEIN, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (10): : 6543 - 6547
[3] ICI-174864 - A HIGHLY SELECTIVE ANTAGONIST FOR THE OPIOID DELTA-RECEPTOR
COTTON, R
GILES, MG
MILLER, L
SHAW, JS
TIMMS, D
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1984, 97 (3-4) : 331 - 332
[4] NALTREXONE, OPIATE ADDICTION, AND ENDORPHINS
GOLD, MS
DACKIS, CA
POTTASH, ALC
STERNBACH, HH
ANNITTO, WJ
MARTIN, D
DACKIS, MP
[J]. MEDICINAL RESEARCH REVIEWS, 1982, 2 (03) : 211 - 246
[5] ANALOGS OF BETA-LPH61-64 POSSESSING SELECTIVE AGONIST ACTIVITY AT MU-OPIATE RECEPTORS
HANDA, BK
LANE, AC
LORD, JAH
MORGAN, BA
RANCE, MJ
SMITH, CFC
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1981, 70 (04) : 531 - 540
[6] HERZ A, 1987, TRENDS MED CHEM, P337
[7] PROPERTIES OF A SELECTIVE KAPPA AGONIST, U-50,488H
LAHTI, RA
VONVOIGTLANDER, PF
BARSUHN, C
[J]. LIFE SCIENCES, 1982, 31 (20-2) : 2257 - 2260
[8] PEPTIDES AS RECEPTOR SELECTIVITY MODULATORS OF OPIATE PHARMACOPHORES
LIPKOWSKI, AW
TAM, SW
PORTOGHESE, PS
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (07) : 1222 - 1225
[9] LIPKOWSKI AW, 1988, PEPTIDE CHEM 1987, P709
[10] LIPOWSKI AW, 1987, POL J PHARM PHARM, V39, P585