ANALYSIS OF THE INVITRO ANTIVIRAL ACTIVITY OF CERTAIN RIBONUCLEOSIDES AGAINST PARA-INFLUENZA VIRUS USING A NOVEL COMPUTER-AIDED RECEPTOR MODELING PROCEDURE

被引：46

作者：

GHOSE, AK ^{[1
]}

CRIPPEN, GM ^{[1
]}

REVANKAR, GR ^{[1
]}

MCKERNAN, PA ^{[1
]}

SMEE, DF ^{[1
]}

ROBINS, RK ^{[1
]}

机构：

[1] UNIV MICHIGAN,COLL PHARM,ANN ARBOR,MI 48109

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 04期

关键词：

D O I：

10.1021/jm00124a005

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：746 / 756

页数：11

共 45 条

[1] CONFORMATIONAL-ANALYSIS OF SUGAR RING IN NUCLEOSIDES AND NUCLEOTIDES - NEW DESCRIPTION USING CONCEPT OF PSEUDOROTATION [J].

ALTONA, C ;

SUNDARALINGAM, M .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (23) :8205-+

[2]

Cohen N. C., 1985, ADV DRUG RES, V14, P41

[3] THE DEVELOPMENT AND USE OF QUANTUM-MECHANICAL MOLECULAR-MODELS .76. AM1 - A NEW GENERAL-PURPOSE QUANTUM-MECHANICAL MOLECULAR-MODEL [J].

DEWAR, MJS ;

ZOEBISCH, EG ;

HEALY, EF ;

STEWART, JJP .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (13) :3902-3909

[4] CRYSTALLINE STRUCTURE OF 5H-PYRAZOLO[3,4-D]PYRIMIDINE-4-THIONE [J].

GADRET, M ;

GOURSOLLE, M ;

LEGER, JM .

ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS, 1974, 30 (JUN15) :1598-1602

[5] GENERAL DISTANCE GEOMETRY 3-DIMENSIONAL RECEPTOR MODEL FOR DIVERSE DIHYDROFOLATE-REDUCTASE INHIBITORS [J].

GHOSE, AK ;

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (07) :901-914

[6] USE OF PHYSICOCHEMICAL PARAMETERS IN DISTANCE GEOMETRY AND RELATED 3-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIPS - A DEMONSTRATION USING ESCHERICHIA-COLI DIHYDROFOLATE-REDUCTASE INHIBITORS [J].

GHOSE, AK ;

CRIPPEN, GM .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (03) :333-346

[7] ATOMIC PHYSICOCHEMICAL PARAMETERS FOR 3-DIMENSIONAL-STRUCTURE-DIRECTED QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS .2. MODELING DISPERSIVE AND HYDROPHOBIC INTERACTIONS [J].

GHOSE, AK ;

CRIPPEN, GM .

JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 1987, 27 (01) :21-35

[8] GEOMETRICALLY FEASIBLE BINDING MODES OF A FLEXIBLE LIGAND MOLECULE AT THE RECEPTOR-SITE [J].

GHOSE, AK ;

CRIPPEN, GM .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1985, 6 (05) :350-359

[9] ATOMIC PHYSICOCHEMICAL PARAMETERS FOR 3-DIMENSIONAL STRUCTURE-DIRECTED QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS .1. PARTITION-COEFFICIENTS AS A MEASURE OF HYDROPHOBICITY [J].

GHOSE, AK ;

CRIPPEN, GM .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1986, 7 (04) :565-577

[10] ATOMIC PHYSICOCHEMICAL PARAMETERS FOR 3-DIMENSIONAL STRUCTURE DIRECTED QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS .3. MODELING HYDROPHOBIC INTERACTIONS [J].

GHOSE, AK ;

PRITCHETT, A ;

CRIPPEN, GM .

JOURNAL OF COMPUTATIONAL CHEMISTRY, 1988, 9 (01) :80-90

← 1 2 3 4 5 →