ON IMPERMEABILITY OF OUTER MITOCHONDRIAL MEMBRANE TO CYTOCHROME C .I. STUDIES ON WHOLE MITOCHONDRIA

被引:115
作者
WOJTCZAK, L
ZALUSKA, H
机构
[1] Department of Biochemistry, Nencki Institute of Experimental Biology
关键词
D O I
10.1016/0005-2736(69)90059-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effect of digitonin on the release from rat-liver mitochondria of adenylate kinase (EC 2.7.4.3) and malate dehydrogenase (EC 1.1.1.37) and on the unmasking of activities of cytochrome oxidase (EC 1.9.3.1) and succinate-cytochrome c reductase with external cytochrome c was studied. Electron micrographs of digiton-in-treated mitochondria were also taken. The results indicate that the unmasking of mitochondrial enzyme activities with exogenous cytochrome c goes parallely with the release of adenylate kinase and the detachment of the outer mitochondrial membrane but does not require the opening of the inner membrane. © 1969.
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页码:64 / &
相关论文
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