COLLAGENOLYTIC ACTIVITY OF A NEW SEMI-ALKALINE PROTEASE FROM ASPERGILLUS-NIGER

被引：14

作者：

BARTHOMEUF, C

POURRAT, H

POURRAT, A

机构：

[1] Laboratoire de Pharmacognosie et Biotechnologie, Laboratoire de Pharmacie Galénique et de Pharmacotechnie, Faculté de Pharmacie, 63001 Clermont-Ferrand Cedex, 28, Place Henri-Dunant

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1992年 / 73卷 / 03期

关键词：

D O I：

10.1016/0922-338X(92)90168-T

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Aspergillus niger LCF 9 synthesizes a new semi-alkaline proteinase with high collagenase activity. The properties and operating range of the enzyme were determined. Tests performed on nine commercial native collagens have showed the enzyme being able to hydrolyze the collagen chain without amino acid being released and to liberate low molecular weight peptides of potential interest in therapeutics.

引用

页码：233 / 236

页数：4

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