RAPID DIAGNOSIS OF TUBERCULOUS MENINGITIS BY A SIMPLIFIED NESTED AMPLIFICATION PROTOCOL

被引：57

作者：

LIU, PYF

SHI, ZY

LAU, YJ

HU, BS

机构：

来源：

NEUROLOGY | 1994年 / 44卷 / 06期

关键词：

D O I：

10.1212/WNL.44.6.1161

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We have developed a simplified protocol based on nested polymerase chain reaction (PCR) for early diagnosis of tuberculous meningitis. Using this protocol, we detected the Mycobacterium tuberculosis genome within 24 hours in the CSF of 19 of 21 patients (90%) with clinically suspected tuberculous meningitis. The PCR results were negative in all 79 nontuberculous meningitis controls.

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页码：1161 / 1164

页数：4

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