COMPARISON OF CALCULATION PROCEDURES FOR ISOTOPE-DILUTION DETERMINATIONS USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY

被引：89

作者：

COLBY, BN ^{[1
]}

MCCAMAN, MW ^{[1
]}

机构：

[1] CITY HOPE NATL MED CTR,DIV NEUROSCI,DUARTE,CA 91010

来源：

BIOMEDICAL MASS SPECTROMETRY | 1979年 / 6卷 / 06期

关键词：

D O I：

10.1002/bms.1200060602

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Several data reduction procedures have been used for converting isotope ratios, determined using gas chromatography mass spectrometry, into mole ratios for the purpose of quantitating organic compounds. In this report, these procedures are shown to be related under certain limiting approximations of original sample and internal standard isotope ratios. With the understanding that some of the procedures involve approximations, the incorporation of related systematic errors into calculated mole ratio values was investigated. The results indicate that certain data reduction procedures allow quantitation over wider mole ratio ranges and with internal standards which contain a significant quantity of unlabeled impurity. Copyright © 1979 Heyden & Son Ltd

引用

页码：225 / 230

页数：6

共 19 条

[11] SIMULTANEOUS MEASUREMENT OF ENDOGENOUS AND DEUTERIUM-LABELED TRACER VARIANTS OF CHOLINE AND ACETYLCHOLINE IN SUBPICOMOLE QUANTITIES BY GAS CHROMATOGRAPHY MASS SPECTROMETRY
JENDEN, DJ
ROCH, M
BOOTH, RA
[J]. ANALYTICAL BIOCHEMISTRY, 1973, 55 (02) : 438 - 448
[12] PETERS DG, 1974, CHEM SEPARATIONS MEA, P32
[13] THEORETICAL CONSIDERATIONS IN STABLE ISOTOPE DILUTION MASS-SPECTROMETRY FOR ORGANIC-ANALYSIS
PICKUP, JF
MCPHERSON, K
[J]. ANALYTICAL CHEMISTRY, 1976, 48 (13) : 1885 - 1890
[14] Rittenberg D, 1940, J BIOL CHEM, V133, P737
[15] REVIEW OF STATISTICAL CONSIDERATIONS INVOLVED IN TREATMENT OF ISOTOPE DILUTION CALIBRATION DATA
SCHOELLER, DA
[J]. BIOMEDICAL MASS SPECTROMETRY, 1976, 3 (06): : 265 - 271
[16] Schoenheimer R, 1939, J BIOL CHEM, V130, P703
[17] SHEMIN D, 1945, J BIOL CHEM, V159, P439
[18] SHOEMAKER DP, 1962, EXPT PHYSICAL CHEM, P34
[19] SIMULTANEOUS ESTIMATION OF PROPOXYPHENE-D0 AND PROPOXYPHENE-D2 LEVELS BY QUANTITATIVE MASS FRAGMENTOGRAPHY - POTENTIAL UTILITY IN MULTI-DOSE INVESTIGATIONS
SULLIVAN, HR
WOOD, PG
MCMAHON, RE
[J]. BIOMEDICAL MASS SPECTROMETRY, 1976, 3 (05): : 212 - 216

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