The multifunctional Ca2+/calmodulin-dependent protein kinases

被引:182
作者
Schulman, Howard [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Pharmacol, Stanford, CA 94305 USA
关键词
D O I
10.1016/0955-0674(93)90111-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Ca2+ mediates the effect of many hormones, neurotransmitters and growth factors on contractility and motility, carbohydrate metabolism, cell cycle, gene expression and neuronal plasticity. Multifunctional Ca2+/calmodulin-dependent (CaM) kinase, CaM kinase la, CaM kinase Ib and CaM kinase IV are four of the kinases that mediate Ca2+-signaling pathways. Recent studies have clarified our understanding of their structure, regulation and function.
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页码:247 / 253
页数:7
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