ONE-POT GRAEBE-ULLMANN SYNTHESIS OF GAMMA-CARBOLINES UNDER MICROWAVE IRRADIATION

被引：63

作者：

MOLINA, A ^{[1
]}

VAQUERO, JJ ^{[1
]}

GARCIANAVIO, JL ^{[1
]}

ALVAREZBUILLA, J ^{[1
]}

机构：

[1] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALCALA DE HENARES, SPAIN

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 16期

关键词：

GRAEBE-ULLMANN SYNTHESIS; GAMMA-CARBOLINES; MICROWAVE IRRADIATION;

D O I：

10.1016/S0040-4039(00)77653-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One-pot efficient and simple synthesis of gamma-carboline derivatives by the Graebe-Ullmann method was conducted in a commercial microwave oven in a few minutes at a low energy level and using erlenmeyer flasks as adequate reaction vessels. Yields are similar to those obtained by conventional heating.

引用

页码：2673 / 2676

页数：4

共 24 条

[1] THE CARBOLINES
ABRAMOVITCH, RA
SPENSER, ID
[J]. ADVANCES IN HETEROCYCLIC CHEMISTRY, 1964, 3 : 79 - 207
[2] ABRAMOVITCH RA, 1992, SYNLETT, P795
[3] ACRAMONE F, 1989, ANTITUMOR NATURAL PR, P1
[4] SYNTHESIS OF 1,4-DIHYDROPYRIDINES UNDER MICROWAVE IRRADIATION
ALAJARIN, R
VAQUERO, JJ
NAVIO, JLG
ALVAREZBUILLA, J
[J]. SYNLETT, 1992, (04) : 297 - 298
[5] MICROWAVE-INDUCED ORGANIC-REACTION ENHANCEMENT CHEMISTRY .4. CONVENIENT SYNTHESIS OF ENANTIOPURE ALPHA-HYDROXY-BETA-LACTAMS
BANIK, BK
MANHAS, MS
KALUZA, Z
BARAKAT, KJ
BOSE, AK
[J]. TETRAHEDRON LETTERS, 1992, 33 (25) : 3603 - 3606
[6] ALKYLATION OF POTASSIUM ACETATE IN DRY MEDIA THERMAL-ACTIVATION IN COMMERCIAL MICROWAVE-OVENS
BRAM, G
LOUPY, A
MAJDOUB, M
GUTIERREZ, E
RUIZHITZKY, E
[J]. TETRAHEDRON, 1990, 46 (15) : 5167 - 5176
[7] Bremer O, 1934, LIEBIGS ANN CHEM, V514, P279
[8] KELLY AH, 1965, CAN J CHEM, V46, P1965
[9] ATTEMPTS TO FIND NEW ANTIMALARIALS .29. THE SYNTHESIS OF VARIOUS DERIVATIVES OF 2-3-BENZ-GAMMA-CARBOLINE
KERMACK, WO
STOREY, NE
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1950, (FEB): : 607 - 612
[10] THE STRUCTURE AND PROPERTIES OF CERTAIN POLYCYCLIC INDOLO-DERIVATIVES AND QUINOLINO-DERIVATIVES .13. THE CYCLISATION OF CERTAIN 4-PYRIDYL-HYDRAZONES AND 4-QUINOLYL-HYDRAZONES
MANN, FG
PRIOR, AF
WILLCOX, TJ
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1959, (DEC): : 3830 - 3834

← 1 2 3 →