DEVELOPMENTAL-CHANGES OF FREQUENCY REPRESENTATION IN THE RAT COCHLEA

被引:53
作者
MULLER, M [1 ]
机构
[1] UNIV FRANKFURT,INST ZOOL,W-6000 FRANKFURT,GERMANY
关键词
RAT; COCHLEA; DEVELOPMENT; PLACE-FREQUENCY MAP; HRP;
D O I
10.1016/0378-5955(91)90147-2
中图分类号
R36 [病理学]; R76 [耳鼻咽喉科学];
学科分类号
100104 ; 100213 ;
摘要
The place-frequency map of the developing rat cochlea was measured by iontophoretic HRP-injections into the ventral cochlear nucleus at electrophysiologically characterized positions. Distribution of retrograde HRP transport in cochlear spiral ganglion cells was analysed by means of a three dimensional reconstruction of the cochlea. Cochlear place-frequency maps were derived in rats of two ages groups: 13 to 22 days, and 36/37 day old animals. These maps were compared with the place-frequency map of adult rats (Muller, 1991). No systematic difference in the place-frequency map between 36/37 day old and adult rats was observed. In animals of the younger age group the place-frequency map (for frequencies above 4 kHz) was shifted towards lower frequencies for a given place along the basilar membrane. The morphological and physiological basis for this frequency shift during development is discussed.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 41 条
[11]   THE COCHLEAR FREQUENCY MAP OF THE MUSTACHE BAT, PTERONOTUS-PARNELLII [J].
KOSSL, M ;
VATER, M .
JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY, 1985, 157 (05) :687-697
[12]   MORPHOLOGICAL-CHANGES IN THE COCHLEA OF THE MOUSE AFTER THE ONSET OF HEARING [J].
KRAUS, HJ ;
AULBACHKRAUS, K .
HEARING RESEARCH, 1981, 4 (01) :89-102
[13]  
KRAUS HJ, 1982, VERH DTSCH ZOOL GES, V279
[14]   STEREOCILIA AND TECTORIAL MEMBRANE-DEVELOPMENT IN THE RAT COCHLEA - A SEM STUDY [J].
LENOIR, M ;
PUEL, JL ;
PUJOL, R .
ANATOMY AND EMBRYOLOGY, 1987, 175 (04) :477-487
[15]   SINGLE-NEURON LABELING AND CHRONIC COCHLEAR PATHOLOGY .3. STEREOCILIA DAMAGE AND ALTERATIONS OF THRESHOLD TUNING CURVES [J].
LIBERMAN, MC ;
DODDS, LW .
HEARING RESEARCH, 1984, 16 (01) :55-74
[16]   SINGLE-NEURON LABELING AND CHRONIC COCHLEAR PATHOLOGY .1. THRESHOLD SHIFT AND CHARACTERISTIC FREQUENCY SHIFT [J].
LIBERMAN, MC .
HEARING RESEARCH, 1984, 16 (01) :33-41
[17]   DEVELOPMENT OF THE PLACE PRINCIPLE - TONOTOPIC ORGANIZATION [J].
LIPPE, W ;
RUBEL, EW .
SCIENCE, 1983, 219 (4584) :514-516
[19]   DEVELOPMENTAL STABILITY OF THE TONOTOPIC ORGANIZATION OF THE CHICKS BASILAR PAPILLA [J].
MANLEY, GA ;
BRIX, J ;
KAISER, A .
SCIENCE, 1987, 237 (4815) :655-656
[20]  
MULLER M, 1990, EXP BRAIN RES, V81, P140