THE TANDEM INSERTION OF ALLYL CARBENOIDS AND ALDEHYDES OR KETONES INTO ZIRCONACYCLOPENTANES - VARIATION OF THE ALLYL MOIETY AND FUNCTIONALIZATION OF THE FINAL CARBON-ZIRCONIUM BOND

被引：16

作者：

LUKER, T ^{[1
]}

WHITBY, RJ ^{[1
]}

机构：

[1] UNIV SOUTHAMPTON,DEPT CHEM,SOUTHAMPTON SO17 1BJ,HANTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)78572-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In situ deprotonation of 2-methyl, 2-chloromethyl-, 2-trimethylsilylmethyl-, and 2-methoxymethoxy-substituted allyl chlorides generates allyl carbenoids which insert into zirconacyclopentanes to afford allyl zirconocenes. Allyl bromides, p-toluenesulphonates, or N,N-diisopropylcarbamates may also be used. The allyl zirconocenes undergo further reaction with aldehydes/BF(3)Et(2)O or ketones to give oxazirconacycles which may be protonated, halogenated, or oxygenated to afford organic products.

引用

页码：9465 / 9468

页数：4

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