ROBERTSONIAN CHROMOSOME FORMATION AND FIXATION - THE GENOMIC SCENARIO

被引:53
作者
REDI, CA [1 ]
GARAGNA, S [1 ]
ZUCCOTTI, M [1 ]
机构
[1] UNIV PAVIA, CNR, CTR STUDIO ISTOCHIM, I-27100 PAVIA, ITALY
关键词
genome; house mouse; karyotype; Robertsonian chromosome; satellite DNA;
D O I
10.1111/j.1095-8312.1990.tb00833.x
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Little agreement exists regarding the biological factors able to promote karyotype diversification; the main efforts, however, to explain the fixation and spreading of rearranged chromosomes are based on population genetics theories. Considering the karyotype structure in relation to genome structuring and functioning we found a close relationship between the rate of karyotypic diversification and the degree of homology of the telomeric DNA sequences in a given genome. We suggest for Robertsonian (Rb) chromosome formation and fixation a molecular mechanism triggered by intrinsic genomic traits: this is able to explain the differential rate at which Rb chromosomes arise in different karyotypes, why the house mouse karyotypic diversification occurs so fast and the présence of so many Rb populations that differ in terms of number and arm‐composition of Rb chromosomes. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码:235 / 255
页数:21
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