MANIPULATION OF GLUTATHIONE CONTENTS FAILS TO ALTER DOPAMINERGIC NIGROSTRIATAL NEUROTOXICITY OF N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IN THE MOUSE

被引：25

作者：

PERRY, TL

YONG, VW

JONES, K

WRIGHT, JM

机构：

来源：

NEUROSCIENCE LETTERS | 1986年 / 70卷 / 02期

关键词：

D O I：

10.1016/0304-3940(86)90474-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

收藏

页码：261 / 265

页数：5

相关论文

共 17 条

[1] GLUTATHIONE MONOETHYL ESTER - PREPARATION, UPTAKE BY TISSUES, AND CONVERSION TO GLUTATHIONE [J].

ANDERSON, ME ;

POWRIE, F ;

PURI, RN ;

MEISTER, A .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1985, 239 (02) :538-548

[2] N-METHYL-4-PHENYLPYRIDINE (MMP+) TOGETHER WITH 6-HYDROXYDOPAMINE OR DOPAMINE STIMULATES CA-2+ RELEASE FROM MITOCHONDRIA [J].

FREI, B ;

RICHTER, C .

FEBS LETTERS, 1986, 198 (01) :99-102

[3]

Griffith O W, 1981, Methods Enzymol, V77, P59

[4] GLUTATHIONE - INTERORGAN TRANSLOCATION, TURNOVER, AND METABOLISM [J].

GRIFFITH, OW ;

MEISTER, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (11) :5606-5610

[5] COMPARATIVE EFFECTS OF ANTIOXIDANTS ON ENZYMES INVOLVED IN GLUTATHIONE METABOLISM [J].

IP, C .

LIFE SCIENCES, 1984, 34 (25) :2501-2506

[6] MANIPULATION OF MOUSE ORGAN GLUTATHIONE CONTENTS .1. ENHANCEMENT BY ORAL-ADMINISTRATION OF BUTYLATED HYDROXYANISOLE AND BUTYLATED HYDROXYTOLUENE [J].

JAESCHKE, H ;

WENDEL, A .

TOXICOLOGY, 1985, 36 (01) :77-85

[7] INHIBITION OF NADH-LINKED OXIDATION IN BRAIN MITOCHONDRIA BY 1-METHYL-4-PHENYL-PYRIDINE, A METABOLITE OF THE NEUROTOXIN, 1-METHYL-4-PHENYL-1,2,5,6-TETRAHYDROPYRIDINE [J].

NICKLAS, WJ ;

VYAS, I ;

HEIKKILA, RE .

LIFE SCIENCES, 1985, 36 (26) :2503-2508

[8] 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) DOES NOT DESTROY NIGROSTRIATAL NEURONS IN THE SCORBUTIC GUINEA-PIG [J].

PERRY, TL ;

YONG, VW ;

ITO, M ;

JONES, K ;

WALL, RA ;

FOULKS, JG ;

WRIGHT, JM ;

KISH, SJ .

LIFE SCIENCES, 1985, 36 (13) :1233-1238

[9] IDIOPATHIC PARKINSONS-DISEASE, PROGRESSIVE SUPRANUCLEAR PALSY AND GLUTATHIONE METABOLISM IN THE SUBSTANTIA-NIGRA OF PATIENTS [J].

PERRY, TL ;

YONG, VW .

NEUROSCIENCE LETTERS, 1986, 67 (03) :269-274

[10] EFFECTS OF N-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE AND ITS METABOLITE, N-METHYL-4-PHENYLPYRIDINIUM ION, ON DOPAMINERGIC NIGROSTRIATAL NEURONS IN THE MOUSE [J].

PERRY, TL ;

YONG, VW ;

JONES, K ;

WALL, RA ;

CLAVIER, RM ;

FOULKS, JG ;

WRIGHT, JM .

NEUROSCIENCE LETTERS, 1985, 58 (03) :321-326