DEPENDENCE OF HYDROGEN-PEROXIDE FORMATION IN RAT-LIVER MICROSOMES ON THE MOLECULAR-STRUCTURE OF CYTOCHROME-P-450 SUBSTRATES - A STUDY WITH BARBITURATES AND BETA-ADRENOCEPTOR ANTAGONISTS

被引：6

作者：

BAST, A ^{[1
]}

GOOSSENS, PAL ^{[1
]}

SAVENIJECHAPEL, EM ^{[1
]}

机构：

[1] STATE UNIV UTRECHT,SUBFAC PHARM,DEPT PHARMACOL,UTRECHT,NETHERLANDS

来源：

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS | 1989年 / 14卷 / 02期

关键词：

D O I：

10.1007/BF03190847

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：93 / 100

页数：8

共 23 条

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[2]

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BAST, A ;

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[5] IS FORMATION OF REACTIVE OXYGEN BY CYTOCHROME-P-450 PERILOUS AND PREDICTABLE [J].

BAST, A .

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[6] CYTOCHROME-P-450 AND GLUTATHIONE - WHAT IS THE SIGNIFICANCE OF THEIR INTERRELATIONSHIP IN LIPID-PEROXIDATION [J].

BAST, A ;

HAENEN, GRMM .

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[7] CALCULATION OF COMPETITIVE-INHIBITION OF SUBSTRATE BINDING TO CYTOCHROME-P-450 ILLUSTRATED BY THE INTERACTION OF D,L-PROPRANOLOL WITH D,L-HEXOBARBITAL [J].

BAST, A ;

NOORDHOEK, J .

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[8] ON THE MECHANISMS OF GLUTATHIONE DEPLETION IN HEPATOCYTES EXPOSED TO MORPHINE AND ETHYLMORPHINE [J].

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TOXICOLOGY, 1986, 42 (01) :13-21

[9] MECHANISMS OF LIPID-PEROXIDATION DEPENDENT UPON CYTOCHROME-P-450 LM2 [J].

EKSTROM, G ;

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[10]

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