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THE WNT FAMILY OF DEVELOPMENTAL REGULATORS

被引：135
作者：
MCMAHON, AP
机构：
来源：
TRENDS IN GENETICS | 1992年 / 8卷 / 07期
关键词：
D O I：
10.1016/0168-9525(92)90122-K
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Since its initial identification in mouse mammary tumors, the proto-oncogene Wnt-1 has been shown to encode a member of a family of putative signalling molecules. Recent work has implicated Wnt-1, and other members of the Wnt gene family, in regulation of a number of basic developmental processes in Drosophila, Xenopus and the mouse. These studies are leading to a new appreciation of the normal and oncogenic actions of Wnt genes.
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页码：236 / 242
页数：7
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