THE WNT FAMILY OF DEVELOPMENTAL REGULATORS

被引：135

作者：

MCMAHON, AP

机构：

来源：

TRENDS IN GENETICS | 1992年 / 8卷 / 07期

关键词：

D O I：

10.1016/0168-9525(92)90122-K

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Since its initial identification in mouse mammary tumors, the proto-oncogene Wnt-1 has been shown to encode a member of a family of putative signalling molecules. Recent work has implicated Wnt-1, and other members of the Wnt gene family, in regulation of a number of basic developmental processes in Drosophila, Xenopus and the mouse. These studies are leading to a new appreciation of the normal and oncogenic actions of Wnt genes.

引用

页码：236 / 242

页数：7

共 59 条

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