PREDICTING FAVORABLE OUTCOME IN IDIOPATHIC WEST SYNDROME

被引:92
作者
DULAC, O [1 ]
PLOUIN, P [1 ]
JAMBAQUE, I [1 ]
机构
[1] HOP ST VINCENT DE PAUL,INSERM,U29,DEPT CLIN NEUROPHYSIOL,F-75674 PARIS 14,FRANCE
关键词
WEST SYNDROME; INFANTILE SPASMS; IDIOPATHIC EPILEPSY; PROGNOSIS; ELECTROENCEPHALOGRAPHY; HYPOARRHYTHMIA;
D O I
10.1111/j.1528-1157.1993.tb00457.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Among 45 patients with cryptogenic West Syndrome (WS) we report 30 with a favorable outcome consisting of normal psychomotor development and cessation of epilepsy with at least 2 years follow-up (mean 4 years 7 months). These favorable patients could be recognized from onset by (a) absence of significant mental regression with a preserved visual function; (b) absence of focal interictal EEG abnormalities after intravenous diazepam; and (c) reappearance of hypsarrhythmia between consecutive spasms of a cluster. The latter criterion requires EEG recording of a series of spasms. The favorable outcome in these patients suggests that they had no cortical brain lesions. This new type of idiopathic epilepsy referred to as idiopathic West syndrome has important prognostic, therapeutic, and etiologic implications.
引用
收藏
页码:747 / 756
页数:10
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