Mutational analysis of protein stability

被引：47

作者：

Matthews, Brian W. ^{[1
]}

机构：

[1] Univ Oregon, Dept Phys, Howard Hughes Med Inst, Eugene, OR 97403 USA

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 01期

关键词：

D O I：

10.1016/0959-440X(91)90005-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability to obtain mutant proteins almost at will, and to subject such variants to detailed structural, thermodynamic and theoretical analyses, is now making it possible to test, in a systematic way, the many longstanding beliefs and prejudices concerning the folding and stability of proteins.

引用

页码：17 / 21

页数：5

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