MEDIAL VESTIBULAR NUCLEUS IN THE GUINEA-PIG .1. INTRINSIC MEMBRANE-PROPERTIES IN BRAIN-STEM SLICES

被引:141
作者
SERAFIN, M
DEWAELE, C
KHATEB, A
VIDAL, PP
MUHLETHALER, M
机构
[1] CTR MED UNIV GENEVA,DEPT PHYSIOL,1 RUE MICHEL SERVET,CH-1211 GENEVA 4,SWITZERLAND
[2] CNRS,PHYSIOL NEUROSENSORIELLE LAB,F-75270 PARIS 06,FRANCE
关键词
LOW THRESHOLD SPIKE; A-LIKE CONDUCTANCE; BURSTS; INVITRO; GUINEA-PIG;
D O I
10.1007/BF00231464
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Intracellular recordings were obtained from medial vestibular nuclei neurones (MVNn) in guinea-pig brainstem slices. Two main distinct neuronal classes were encountered. Type A MVNn (32.3%) were characterized by a broad action potential followed by a deep single afterhyperpolarization, a transient A-like rectification. and a single range of firing in response to current injection. Type B MVNn (47.1%), in contrast, were distinguished by the presence of a thin action potential followed first by a fast and then by a delayed and slower afterhyperpolarization. In addition, they displayed a secondary range of firing in their response to current injection. A majority of B MVNn also had either subthreshold plateau potentials or low threshold spike bursts or a combination thereof. A third, non-homogeneous class of cells, could not be fitted into either one of the two main classes (20.6%, type C MVNn).
引用
收藏
页码:417 / 425
页数:9
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