THE SYNTHESIS OF A C-9-C-17 FRAGMENT OF DISCODERMOLIDE

被引：40

作者：

EVANS, PL ^{[1
]}

GOLEC, JMC ^{[1
]}

GILLESPIE, RJ ^{[1
]}

机构：

[1] ROUSSEL LABS LTD,SWINDON SN3 5BZ,WILTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 50期

关键词：

D O I：

10.1016/S0040-4039(00)61480-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric synthesis of a synthetically useful fragment corresponding to the C-9-C-17 region of the immunosuppressant lactone discodermolide is reported. The route incorporates the use of an unsaturated lactone to provide a trisubstituted olefin with absolute control of geometry.

引用

页码：8163 / 8166

页数：4

共 10 条

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