MULTIFUNCTIONAL MOLECULAR RECOGNITION OF ATP, ADP AND AMP NUCLEOTIDES BY THE NOVEL RECEPTOR 2,6,10,13,17,21-HEXAAZA[22]METACYCLOPHANE

被引：72

作者：

AGUILAR, JA

GARCIAESPANA, E

GUERRERO, JA

LUIS, SV

LLINARES, JM

MIRAVET, JF

RAMIREZ, JA

SORIANO, C

机构：

[1] UNIV VALENCIA,DEPT INORGAN CHEM,E-46100 BURJASSOT,SPAIN

[2] UNIV VALENCIA,FAC PHARM,DEPT ORGAN CHEM,E-46100 BURJASSOT,SPAIN

[3] UNIV JAUME 1,DEPT EXPTL SCI,ORGAN CHEM LAB,E-12080 CASTELLO DE PLANA,SPAIN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 21期

关键词：

D O I：

10.1039/C39950002237

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The novel cyclophane receptor 2,6,10,13,17,21-hexaaza[22]metacyclophane L presents a molecular architecture which enables recognition in aqueous solution of ATP, ADP and AMP through electrostatic, hydrogen bonding and pi-stacking interactions; electrostatic interactions occur between the polyammonium sites of L and the phosphate chain of the nucleosides, and pi-stacking interactions occur between the m-phenylene subunit incorporated in the receptor as a non-pendant integral part of the macrocyclic framework and the adenine ring of the nucleotides.

引用

页码：2237 / 2239

页数：3